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M94A2557.TXT
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1994-10-25
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Document 2557
DOCN M94A2557
TI Improving pediatric AIDS case definition in Sao Paulo, Brasil.
DT 9412
AU Gianna MC; Barbieri DD; Niskier H; Ruiz EA; Domingues CS; Santos LF;
Santos NJ; Epidemiologic Surveillance Center, Sao Paulo, Brazil.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):277 (abstract no. PC0030). Unique
Identifier : AIDSLINE ICA10/94370018
AB OBJECTIVE: Contribute to the improvement of the sensitivity of AIDS case
definition in children to decrease undernotifying METHODS: A
retrospective study of 299 (34%) of the 875 cases of AIDS notified in
children under 15 in the State of Sao Paulo since 1984 was performed. We
registered all clinical manifestations (CM) and opportunistic infections
(OI) according to age groups: (1; 1-4; 5-9; 10-14 years. RESULTS: The
most frequent CM were fever (44%), weight loss (40%), diarrhea (39%),
hepatomegaly (37%) and growth impairment (34%). The most frequent OI
were oral candidiasis (53.5%), bacterial pneumonia (33%), Pneumocystis
carinii pneumonia (22.7%), tuberculosis (18.5%), and otitis (11.5%). CM
were evenly distributed among the age groups studied. The frequency of
OI differed however according to age, as children in the 10-14 age group
presented OI more similar to AIDS in adults. CONCLUSION: The current CDC
definition of AIDS case in children is not sensitive enough for defining
cases in Brazil. The description of the most frequent CM and OI shows
that new criteria for defining case in our environment is necessary.
DE Acquired Immunodeficiency Syndrome/*DIAGNOSIS Adolescence AIDS-Related
Opportunistic Infections/DIAGNOSIS Brazil Child Child, Preschool
Human Infant Retrospective Studies Sensitivity and Specificity
MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).